Research Article

Stratification of Highest-Risk Patients with Chronic Skin Ulcers in a Stanford Retrospective Cohort Includes Diabetes, Need for Systemic Antibiotics, and Albumin Levels

Table 4

Therapeutic interventions in patients with healing and non-healing wounds.

Healing wound ( )Nonhealing wound ( ) value

Topical treatments (%)66/68 (97.1%)63/67 (94.0%)0.44
Systemic antibiotics (%)38/68 (55.9%)55/67 (82.1%)0.001*
Wound debridement (%)15/68 (25.9%)29/67 (43.3%)0.008*
Peripheral revascularization (%)16/68 (23.5%)18/67 (26.9%)0.65
Compression stockings (%)4/68 (5.9%)6/67 (8.9%)0.53
Venous ablation or stripping (%)5/68 (7.4%)0/67 (0%)0.058
Skin graft (%)4/68 (5.9%)6/67 (8.9%)0.53
Wound vacuum (%)4/68 (5.9%)3/67 (4.5%)0.99
Hyperbaric oxygen (%)1/68 (1.4%)1/67 (1.5%)0.99

1Healing wounds were those that healed within 1 year of followup. Non-healing wounds were defined as wounds that required amputation or did not heal after 1 year of followup. 2Topical treatments included but were not limited to wet-dry dressings, papain ointment, topical antibiotics, silvadene ointment, whirlpool treatment, accuzyme application, and Dakin's soaks. 3Systemic antibiotics refer to antibiotics administered orally or intravenously. 4Wound debridement refers to surgical debridement or debridement in physician's office. 5Peripheral revascularization refers to angioplasty or bypass graft of peripheral arteries. 6Skin graft referred to human skin autograft or synthetic skin graft/Dermagraft. 7Hyperbaric oxygen refers to treatment in hyperbaric oxygen chamber.
*indicates statistical significance at .