|: number of rats. |
Statistically different relative to group 2, .
Statistically different relative to group 1, .
Healthy control: healthy, nonulcerated control rats.
Group 1 (ulcerated rats sacrificed 4 days after acetic acid ulcer induction), showing a deep large ulcer (about 81 mm2), with raised edges and sclerous interior.
Group 2 (ulcerated rats given vehicle for 14 days following ulcer induction).
Groups 3, 4, and 5 ulcerated rats treated with 125, 250, and 500 mg/kg bw of extract, respectively, for 14 d after day 4 of ulcer establishment.
Positive control rat given ranitidine (50 mg/kg bw) for 14 d after ulcer establishment.