Comparison of the Manual, Semiautomatic, and Automatic Selection and Leveling of Hot Spots in Whole Slide Images for Ki-67 Quantification in Meningiomas

Figure 6

The mean and standard deviation of the scoring Ki-67 index for all 50 examined glass slides and their WSI derived from meningioma patients. Data are grouped according to the types of measurements, grade of malignance (grade I, grade II, and grade III), and type of sample preparation method (sets A and B). In each of the three bars the first, blue bar shows the result for the manual microscopic expert score and the second, red bar shows the result for the mean of the pathologists’ quantifications using WSI, while the third, green bar presents results for the proposed automated method.