Iron Overload in Sickle Cell Disease

Table 2

Indications for chelation therapy in SCD.

Test	Adult patients	Pediatric patients
Transfusional iron load	20 to 30 units	>100 mg/kg
Serum ferritin	>3000 ng/mL, 1500–3000 ng/mL: equivocal	>3000 ng/mL, 1500–3000 ng/mL: equivocal
HIC	>7–9 mg/g dry weight	>7–9 mg/g dry weight