Iron Loading and Overloading due to Ineffective Erythropoiesis

Table 1

Ineffective erythropoiesis associated with iron overload in absence of transfusion.

Erythroid disorder	Defect	Reference
Thalassemia syndromes	Globin chain imbalance.	[67, 86]
Sideroblastic Anemia (inherited or acquired)	Iron accumulation in mitochondria.	[23, 70, 87, 88]
Dyserythropoietic Anemia (Types I and II)	Nuclear and membrane defects.	[26, 27, 69]