Perioperative Anesthesiological Management of Patients with Pulmonary Hypertension

Table 11

Specific interventions for therapy of intra- and/or postoperative increase of pulmonary arterial pressure (mod. [30, 31, 38, 39, 48, 59, 60]).

Reduction of right-ventricular afterload:
Intravenous vasodilation
(1) Milrinone	50 μg/kgBW bolus, followed by 0,5–0,75 μg/kgBW/min continuously
(2) Dobutamine	2–5 μg/kgBW/min continuously
(3) Prostacyclin	4–10 ng/kgBW/min continuously
(4) Na-nitruprusside	0,2–0,3 μg/kgBW/min continuously
(5) Nitroglycerine	2–10 μg/kgBW/min continuously
Pulmonary-selective inhalative vasodilatation
(1) Iloprost	5–10 μg for 10–15 min (by untrasonic nebulizer)
(2) Nitrogen monoxide	0,5–20 ppm continuously
(3) Prostacyclin	30–40 ng/kgBW/min continuously
(4) Milrinone	2 mg (−5 mg) for 10–15 min (diluted in 10–15 mL NaCl0,9%)