The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections

Table 2

Spectrum of activity of antifungals against fungi causing invasive disease in critical care [13, 14].

Antifungal agent	Aspergillus	Candida	Cryptococcus	Zygomyces (Mucor, Rhizopus)	Fusarium	Scedosporium
Amphotericin B	+	+	+	+	−	−
Fluconazole	−	+	+	−	−	−
Itraconazole	+	+	+	−	+/−	−
Voriconazole	+	+	+	−	+	+
Posaconazole	+	+	+	+	+	+
Caspofungin	+	+	−	−	−	−
Micafungin	+	+	−	−	−	−
Anidulafungin	+	+	−	−	−	−