| | Gene polymorphism | Allele change | Minor allele frequency | Grouped genotypes | Bleeding complications, number (%) | OR (95% CI) | P | Presence
(n = 21) | Absence
(n = 121) |
| | VKORC1 | C>T | 0.113 | CC, CT | 3 (14.3) | 27 (22.3) | 1 | 0.405 | | rs9934438 | | | TT | 18 (85.7) | 94 (77.7) | 1.72 (0.47-6.29) | | | CYP2C9 | A>C | 0.043 | AA | 18 (85.7) | 111 (92.5) | 1 | 0.304 | | rs1057910 | | | AC, CC | 3 (14.3) | 9 (7.5) | 2.06 (0.51-8.32) | | | 8q24 | G>T | 0.384 | GG | 4 (19.0) | 16 (13.2) | 1 | 0.479 | | rs6983267 | | | GT, TT | 17 (81.0) | 105 (86.8) | 0.65 (0.19-2.17) | | | 8q24 | A>C | 0.162 | AA | 0 (0.0) | 2 (1.7) | 1 | 0.553 | | rs1447295 | | | AC, CC | 21 (100.0) | 119 (98.3) | 0.98 (0.96-1.01) | | | 8q24 | A>G | 0.162 | AA | 0 (0.0) | 5 (4.1) | 1 | 0.343 | | rs4242382 | | | AG, GG | 21 (100.0) | 116 (95.9) | 0.96 (0.92-1.00) | | | 8q24 | C>A | 0.155 | CC | 0 (0.0) | 4 (3.3) | 1 | 0.398 | | rs4242384 | | | CA, AA | 21 (100.) | 117 (96.7) | 0.97 (0.94-1.00) | | | 8q24 | T>G | 0.141 | TT | 0 (0.0) | 5 (4.1) | 1 | 0.343 | | rs7837688 | | | TG, GG | 21 (100.0) | 116 (95.9) | 0.96 (0.92-1.00) | | | 8q24 | A>G | 0.278 | AA, AG | 18 (85.7) | 113 (93.4) | 1 | 0.225 | | rs16902094 | | | GG | 3 (14.3) | 8 (6.6) | 2.35 (0.57-9.71) | | | 8q24 | T>C | 0.454 | TT, TC | 16 (76.2) | 99 (81.8) | 1 | 0.544 | | rs445114 | | | CC | 5 (23.8) | 22 (18.2) | 1.41 (0.47-4.25) | | | 8q24 | T>C | 0.304 | TT, TC | 19 (95.0) | 105 (87.5) | 1 | 0.329 | | rs1456315 | | | CC | 1 (5.0) | 15 (12.5) | 0.37 (0.05-2.96) | | | 8q24 | A>C | 0.254 | AA, AC | 17 (81.0) | 116 (95.9) | 1 | 0.010 | | rs6983561 | | | CC | 4 (19.0) | 5 (4.1) | 5.45 (1.33-22.36) | | | 8q24 | C>A | 0.261 | CC, CA | 17 (81.0) | 116 (95.9) | 1 | 0.010 | | rs16901979 | | | AA | 4 (19.0) | 5 (4.1) | 5.46 (1.33-22.36) | | | 8q24 | C>T | 0.261 | CC, CT | 17 (81.0) | 116 (95.9) | 1 | 0.010 | | rs10505483 | | | TT | 4 (19.0) | 5 (4.1) | 5.46 (1.33-22.36) | | | 8q24 | A>G | 0.292 | AA, AG | 17 (81.0) | 106 (87.6) | 1 | 0.409 | | rs13252298 | | | GG | 4 (19.0) | 15 (12.4) | 1.66 (0.49-5.61) | | | 8q24 | C>T | 0.340 | CC, CT | 17 (81.0) | 107 (89.2) | 1 | 0.286 | | rs1016343 | | | TT | 4 (19.0) | 13 (10.8) | 1.94 (0.56-6.64) | | | 8q24 | A>G | 0.391 | AA, AG | 12 (57.1) | 77 (63.6) | 1 | 0.570 | | rs10505477 | | | GG | 9 (42.9) | 44 (36.4) | 1.31 (0.51-3.36) | | | 8q24 | G>T | 0.261 | GG, GT | 17 (81.0) | 112 (92.6) | 1 | 0.089 | | rs9642880 | | | TT | 4 (19.0) | 9 (7.4) | 2.93 (0.81-10.57) | | | 8q24 | A>G | 0.465 | AA, AG | 19 (90.5) | 81 (66.9) | 1 | 0.029 | | rs13281615 | | | GG | 2 (9.5) | 40 (33.1) | 0.21 (0.05-0.96) | | | 8q24 | T>C | 0.170 | TT, TC | 21 (100.0) | 113 (94.2) | 1 | 0.256 | | rs1562430 | | | CC | 0 (0.0) | 7 (5.8) | 0.94 (0.90-0.98) | | | 8q24 | A>G | 0.278 | AA | 3 (14.3) | 7 (5.8) | 1 | 0.160 | | rs7014346 | | | AG, GG | 18 (85.7) | 114 (94.2) | 0.37 (0.09-1.57) | | | Myc | C>T | 0.113 | CC, CT | 21 (100.0) | 120 (99.2) | 1 | 0.676 | | rs4645957 | | | TT | 0 (0) | 1 (0.8) | 0.99 (0.98-1.01) | | | Myc | C>T | 0.150 | CC, CT | 20 (95.2) | 117 (98.3) | 1 | 0.369 | | rs4645948 | | | TT | 1 (4.8) | 2 (1.7) | 2.93 (0.25-33.79) | | | Myc | T>C | 0.011 | TT | 21 (100.0) | 118 (97.5) | 1 | 0.466 | | rs4645962 | | | TC, CC | 0 (0.0) | 3 (2.5) | 0.98 (0.95-1.01) | | | Myc | C>T | 0.302 | CC | 8 (42.1) | 55 (49.1) | 1 | 0.572 | | rs4645943 | | | CT, TT | 11 (57.9) | 57 (50.9) | 1.33 (0.50-3.55) | | | Myc | C>T | 0.159 | CC | 11 (61.1) | 84 (73.7) | 1 | 0.270 | | rs4645974 | | | CT, TT | 7 (38.9) | 30 (26.3) | 1.78 (0.63-5.02) | |
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