Effects of Polymorphisms in Myc-Related Genes on Bleeding Complications in Patients with Stable Warfarin Responses

Table 3

Multivariate analysis to identify predictors for bleeding complications at a therapeutic INR.

Variables	Adjusted OR (95% CI)	Attributable risk (%)	NNG
Atrial fibrillation	5.50 (1.30-23.36)	81.83
8q24; rs6983561, CC	27.64 (3.63-210.29)	96.38	36.8
8q24; rs13281615, AA, AG	10.00 (1.47-68.6)	90.00	8.3

Logistic regression analyses were carried out with variables of sex, age, atrial fibrillation, rs6983561, and rs13281615.
p < 0.05; p < 0.01.
Number needed to genotype (NNG) was calculated with the formula 1/(attributable risk × proportion of patients with both bleeding complications and risk genotypes).