The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Table 8

Comparison of NF-κB absolute pixel density between experimental groups.

Comparison Groups	P Value
Control x Low Dose Pitavastatin	1.000
Control x High Dose Pitavastatin	0.465
Control x TNF-α	0.006
Control x Low Dose Pitavastatin + TNF-α	0.034
Control x High Dose Pitavastatin + TNF-α	0.948
Control x DMSO	0.568
Low Dose Pitavastatin x High Dose Pitavastatin	0.361
Low Dose Pitavastatin x TNF-α	0.004
Low Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.077
Low Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.796
Low Dose Pitavastatin x DMSO	0.568
High Dose Pitavastatin x TNF-α	0.011
High Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.285
High Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.558
High Dose Pitavastatin x DMSO	0.808
Low Dose Pitavastatin + TNF-αx TNF-α	0.099
Low Dose Pitavastatin + TNF-αx High Dose Pitavastatin + TNF-α	0.123
Low Dose Pitavastatin + TNF-αx DMSO	0.153
High Dose Pitavastatin + TNF-αx TNF-α	0.039
High Dose Pitavastatin + TNF-αx DMSO	0.862
TNF-α x DMSO	0.004

NF-κB, nuclear factor-kappa B; TNF-α, tumor necrosis factor-α; DMSO, dimethyl sulfoxide.