Research Article
Safety and Tolerability of Initiating Maximum-Dose Sacubitril-Valsartan in Patients on Target Dose Renin-Angiotensin System Inhibitors
Table 2
Reasons for discontinuation of sacubitril-valsartan within first year.
| Number | Patient | Reason for discontinuation |
| 1 | 87-year-old man | Dizziness, syncope, and a slowly developing itching rash | 2 | 82-year-old woman | Irritated bowels | 3 | 81-year-old man | Slowly developing itching rash | 4 | 80-year-old man | Progressive kidney failure | 5 | 79-year-old man | Orthostatic hypotension, even after dose reduction | 6 | 76-year-old man | Coughing | 7 | 77-year-old man | Progressive kidney failure | 8 | 76-year-old man | Slowly developing itching rash | 9 | 69-year-old man | Decided he did not want to continue with medication that is not currently endorsed by national guidelines |
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