Research Article

Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study

Table 1

Characteristics of all 23 patients.

Patients Laboratory findings
At the first examinationPeak valueAt the last examination
(bottom value only as for platelet count)

Gender (male)12 (52.2%)
Age (years)58.2 ± 8.5NA68.8 ± 9.5
AST (U/L)40 ± 2657 ± 3028 ± 10
ALT (U/L)49 ± 3572 ± 3526 ± 12
GGT (U/L)NA94 ± 8345 ± 44
FIB4 index1.66 ± 0.782.84 ± 1.342.04 ± 0.82
AAR0.88 ± 0.221.52 ± 0.341.17 ± 0.31
Platelet count (×109/L)215 ± 68165 ± 45207 ± 63
Type IV collagen 7S (ng/mL)NA5.2 ± 2.04.4 ± 1.4
M2BPGiNA1.09 ± 0.860.88 ± 0.74

Mean ± SD

Continuous variables were shown as mean ± standard deviation. At the last examination both type IV collagen 7S and M2BPGi were examined in all 23 patients. , number of patients; NA, no analysis; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transpeptidase; AAR, AST/ALT ratio; M2BPGi, Mac-2 binding protein.