Canadian Journal of Infectious Diseases and Medical Microbiology / 2018 / Article / Tab 3 / Research Article
Isolation of Extended-Spectrum β -lactamase- (ESBL-) Producing Escherichia coli and Klebsiella pneumoniae from Patients with Community-Onset Urinary Tract Infections in Jimma University Specialized Hospital, Southwest Ethiopia Table 3 Resistance profiles of ESBL-producing and non-ESBL-producing Escherichia coli and Klebsiella pneumoniae isolates in JUSH, Southwest of Ethiopia.
Antibiotics Total R (N %) ESBL-positive (n = 17) (N %) ESBL-negative (n = 57) (N %) valueR R S R S Cefotaxime 18 (24.3%) 17 (100%) 0 1(1.8%) 56 (98.2%) 0.001 Ceftriaxone 17 (23.0%) 17 (100%) 0 0 57 (100%) 0.001 Ceftazidime 16 (21.6%) 12 (70.6%) 5 (29.4%) 4 (7.0%) 53 (93.0%) 0.001 AMC 27 (36.5%) 14 (82.4%) 3 (17.6%) 13 (22.8%) 44 (77.2%) 0.001 Cephalothin 53 (71.6%) 17 (100%) 0 36 (63.2%) 21 (36.8%) 0.051 Ampicillin 74 (100%) 17 (100%) 0 57 (100%) 0 — Gentamicin 17 (23%) 11 (64.7%) 6 (35.3%) 6 (10.5%) 51(89.5%) 0.001 Amikacin 7 (9.5%) 4 (23.5%) 13 (76.5%) 3 (5.3%) 54 (94.7%) 0.024 NA 38 (51.4%) 13 (76.5%) 4 (23.5%) 25 (43.9%) 32 (56.1%) 0.001 CIP 24 (32.4%) 13 (76.5%) 4 (23.5%) 11 (19.3%) 46 (80.7%) 0.001 Norfloxacin 23 (31.1%) 13 (76.5%) 4 (23.5%) 10 (17.5%) 47 (82.5%) 0.001 SXT 41 (55.4%) 14 (82.4%) 3(17.6%) 27 (47.4%) 30 (52.6%) 0.001 Tetracycline 45 (60.8%) 14 (82.4%) 3 (17.6%) 31 (54.4%) 26 (45.6%) 0.021 C 30 (40.5%) 12 (70.6%) 5 (29.4%) 18 (31.6%) 39 (68.4%) 0.004 Imipenem 0 0 17 (100%) 0 57 (100%) —
R: resistant, S: sensitive, AMC: amoxicillin-clavulanic acid, NA: nalidixic acid, CIP: ciprofloxacin, SXT: trimethoprim-sulfamethoxazole, C: chloramphenicol.