Alleviation of Anxiety/Depressive-Like Behaviors and Improvement of Cognitive Functions by Lactobacillus plantarum WLPL04 in Chronically Stressed Mice

Figure 3

L. plantarum WLPL04 treatment rescues the negative change in the intestinal microbiota. (a) Aggregate microbiota composition at the phylum level in the fecal samples of experimental mice. Chronic stress significantly reduces the number of Firmicutes, and such negative effect is reversed by the L. plantarum WLPL04 treatment. Bacterial diversity and species richness as indicated by the (b) Chao1 and the (c) Shannon indices. The chronic stress tends to destroy the diversity and destroy the species richness, and such negative effects are rescued by the L. plantarum WLPL04 treatment. n = 12 mice per group.

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