Modulation of Short-Chain Fatty Acids as Potential Therapy Method for Type 2 Diabetes Mellitus

<div>Signaling pathways of GPR41 and GPR43 activated by SCFAs. The signaling pathway downstream of each receptor is illustrated. AC, adenylate cyclase; [Ca<sup>2+</sup>]<sub>i</sub>, intracellular Ca<sup>2+</sup> concentration; GPR, G protein-coupled receptor; IP3, inositol trisphosphate; PLC, phospholipase C; SCFAs, short-chain fatty acids.</div>

Canadian Journal of Infectious Diseases and Medical Microbiology

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Figure 3

Figure 3: Modulation of Short-Chain Fatty Acids as Potential Therapy Method for Type 2 Diabetes Mellitus 