Review Article

How to Modulate Tumor Hypoxia for Preclinical In Vivo Imaging Research

Figure 3

In vivo hypoxia modulation. Overview of the different experimental techniques and study designs that may be applicable for manipulating the tumor oxygenation state for hypoxia research. (a) Tumor physiological parameters. (b) Animal physiological parameters. (c) External interventions. (d) Pharmacological interventions.