Toward the Optimization of (+)-[¹¹C]PHNO Synthesis: Time Reduction and Process Validation

Table 1

Starting activity, activity yield, number of experiments, and success rate of the studied experimental setups.

Temperature at LAH addition (°C)	Starting activity (EOB) (GBq)	Activity yield (GBq)	n	Success rate (%)
22	120 ± 15	1.7 ± 1.0	16	89
−15	122 ± 13	0.7 ± 0.2	9	82
−40	113 ± 8	0.6 ± 0.1	3	100