Evaluation of the Impact of Magnetic Resonance Imaging (MRI) on Gross Tumor Volume (GTV) Definition for Radiation Treatment Planning (RTP) of Inoperable High Grade Gliomas (HGGs)

Table 3

Selected series assessing target definition in HGGs with incorporation of MRI into RTP.

Authors	Study year	Number of patients with HGG	Mean/median volume of GTV defined on CT only (cc)	Mean/median volume of GTV defined on CT and MRI (cc)	p
Weltens et al. [19]	2001	5	59.5 cc	69.6 cc	< 0.05
Datta et al. [20]	2008	16	50.72 cc	62.35	0.044
Fiorentino et al. [21]	2013	30	36.48 cc	52.44	0.0003
Current study		25	65.3 cc	76.1 cc	< 0.05