Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection: A Case Report

Table 2

Postmortem detection of HSV-1 DNA in various tissues. Results of the semiquantitative PCR performed after mortem detecting virus DNA in all tested tissues except for cerebrum and cerebellum (𝑐_T-value: cycle threshold).

Tissue	Herpes simplex virus-1 DNA; (qualitative)	𝑐T-values in RT-PCR
Spleen	++	32
Liver	++	30
Left Kidney	++	30
Retroperitoneal lymphoma	++	33
Lymph nodes	++	33
Bone marrow	+	36
Muscle	++	33
Cerebrum	—	—
Cerebellum	—	—
Oral mucosa	++++	24
Trachea	++++	23
Right main bronchus	++++	23
Right lung (lower lobe)	+++	28
Right lung (upper lobe)	++	31
Right ventricle	+++	26
Left ventricle	++	30
Stomach	+++	28
Small intestine	+++	27
Colon	++	34