Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients

Table 1

Clinical findings of previous reported cases of postinfluenza vaccination thrombocytopenia.

Study design	Reference	Number of ITP patients	Patient characteristics	History	Duration of thrombocytopenia from vaccination	Platelet count (/μL)	Elevation of PAIgG level	Treatment	Outcome
Case-control study	Jadavji et al., 2003 [1]	2	NA	NA	10 days; 14 days	NA; NA	NA; NA	NA; NA	FR; c-ITP
	Garbe et al., 2012 [14]	3	NA	NA	NA	NA	NA	NA	NA
	Grimaldi-Bensouda et al., 2012 [2]	43	NA	NA	<12 mo	NA	NA	NA	NA
Case report	Kelton, 1981 [3]	1	38-year-old, male	COPD	12 days	32000	Positive	Steroids	FR
	Casoli and Tumiati, 1989 [4]	1	32-year-old, male	None	15 days	NA	NA	Steroids	FR
	Granier et al., 2003 [5]	1	72-year-old, female	None	8 days	3000	Positive	Steroids	FR
	Ikegame et al., 2006 [6]	1	19-year-old, female	ALL (post-BMT)	14 days	10000	Positive	IVIG, steroids, and eradication	FR
	Tishler et al., 2006 [7]	1	68-year-old, male	HT	14 days	3000	NA	IVIG and steroids	FR
	Mamori et al., 2008 [8]	1	75-year-old, female	AILD	7 days	5000	Positive	Steroids	FR
	Tsuji et al., 2009 [9]	1	79-year-old, male	DM	4 days	4000	Negative	IVIG and steroids	c-ITP
	Mantadakis et al., 2010 [10]	1	3-year-old, male	None	26 days	11000	NA	IVIG	FR
	Shlamovitz and Johar, 2013 [11]	1	50-year-old, man	None	4 days	<5000	NA	IVIG and steroids	FR
			81-year-old, female	HT	28 days	27000	Positive	Eradication	FR
	Nagasaki 2016	3	75-year-old, female	AP and LD	35 days	5000	Positive	Steroids and eradication	FR
			87-year-old, female	None	14 days	2000	Positive	Steroids	FR

ITP: immune thrombocytopenic purpura; NA: not applicable; COPD: chronic obstructive pulmonary disease; ALL: acute lymphoblastic leukemia; BMT: bone marrow transplantation; HT: hypertension; AILD: autoimmune liver disease; DM: diabetes mellitus; HL: hyperlipidemia; AP: angina pectoris; IVIG: intravenous immunoglobulin; FR: full recovery; c-ITP: chronic-ITP.