Research Article
Using Fresh Frozen Plasma for Acute Airway Angioedema to Prevent Intubation in the Emergency Department: A Retrospective Cohort Study
Table 1
Patient characteristics.
| | Parameter | FFP
() | No FFP
() | value |
| | Age, years, mean (SD) | 62.9 (11.1) | 61.2 (15.4) | 0.64 | | Male gender, (%) | 10 (50) | 50 (46) | 0.81 | | Race, (%) | | | 1.00 | | Caucasian | 3 (15) | 18 (17) | | | African-American | 17 (85) | 89 (83) | | | Admission type, (%) | | | — | | ED | 19 (95) | 98 (90) | | | ECF | 1 (5) | 5 (5) | | | Direct | 0 (0) | 5 (5) | | | Comorbidities, (%) | | | | | Diabetes mellitus | 9 (45) | 28 (26) | 0.11 | | Hypertension | 19 (95) | 97 (90) | 0.69 | | CHF | 2 (10) | 7 (7) | 0.63 | | Asthma | 1 (5) | 12 (11) | 0.69 | | COPD | 6 (30) | 26 (24) | 0.58 | | OSA | 4 (20) | 8 (7) | 0.09 | | CKD | 1 (5) | 20 (19) | 0.19 | | Cancer | 0 (0) | 10 (9) | 0.36 | | History of allergies, (%) | 20 (100) | 106 (98) | 1.00 | | Number of allergies, mean (SD) | 2.0 (1.0) | 2.4 (1.6) | 0.34 | | History of ACE-I, (%) | 18 (90) | 92 (85) | 0.74 | | History of angioedema, (%) | 6 (30) | 26 (24) | 0.58 | | History of intubation, (%) | 3 (15) | 4 (4) | 0.08 |
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ACE-I, ACE inhibitor; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; ECF, extended care facility; ED, emergency department; FFP, fresh frozen plasma; OSA, obstructive sleep apnea; SD, standard deviation.
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