Cancer Cachexia: Mechanisms and Clinical Implications

Table 3

Endpoints for evaluating interventions in cancer cachexia.

Clinical	Functional	Biochemical
Nutritional status	Performance score (ECOG; Karnofsky)	Plasma fatty acid composition
Tolerance of diet	Quality of life scores	Pro-inflammatory cytokines
GI symptoms	Appetite	Acute phase protein reactants
Infections	Fatigue
Survival	Physical activity as measured electronically [22]
	Muscle strength