Research Article

Associations between White Blood Cell Count and the Development of Incidental Nonalcoholic Fatty Liver Disease

Table 1

Baseline characteristics of study subjects according to white blood cell quartiles.

Women (cells/L)Q1 ()Q2 ()Q3 ()Q4 () for trend

Age, years0.243
Body mass index, kg/m2<0.001
Waist circumference, cm0.017
ALT, IU/L0.090
Fasting glucose, mg/dL0.010
Triglycerides, mg/dL<0.001
HDL cholesterol, mg/dL<0.001
White blood cell counts, cells/μL<0.001
Current smoking, %6 (1.9)11 (3.5)2 (0.6)11 (3.5)0.072
Hypertension, %32 (10.2)28 (8.9)24 (7.7)43 (13.7)0.071
5 yr_NAFLD, %29 (9.3)55 (17.6)58 (17.9)78 (24.9)<0.001

Men (cells/μL)Q1 ()Q2 ()Q3 ()Q4 () for trend

Age, years0.171
Body mass index, kg/m2<0.001
Waist circumference, cm<0.001
ALT, IU/L0.012
Fasting glucose, mg/dL0.020
Triglycerides, mg/dL<0.001
HDL cholesterol, mg/dL<0.001
White blood cell counts, cells/μL<0.001
Current smoking, %34 (14.7)46 (19.7)68 (28.8)103 (44.0)<0.001
Hypertension, %32 (13.9)47 (20.1)46 (19.5)51 (21.8)0.145
5 yr_NAFLD, %58 (25.1)77 (32.9)91 (38.6)113 (48.3)<0.001

Values are expressed as the mean ± standard deviation or number (%).
ALT: alanine aminotransferase; NAFLD: nonalcoholic fatty liver disease; HDL: high density lipoprotein.