Treatment of Bacterial Vaginosis: A Multicenter, Double-Blind, Double-Dummy, Randomised Phase III Study Comparing Secnidazole and Metronidazole

Table 5

Clinical cure with bacteriological improvement and/or cure at D14 and D28 in the mITT population.

	Therapeutic success (%)		Clinical cure with bacteriological cure
	(i.e., clinical and bacteriological cure)		or improvement* (%)
	D14	D28	D14	D28
Secnidazole	65.0%	60.1%	72%	69%
(𝑛=243)	(158/243)	(146/243)	(𝑛=174)	(𝑛=167)
Metronidazole	66.2%	59.5%	72%	67%
(𝑛=237)	(157/237)	(141/237)	(𝑛=171)	(𝑛=158)
95% CI Secnidazole-Metronidazole	[−0.097; 0.073]	[−0.082; 0.094]

*Bacteriological improvement defined as a nugent score between 3 and 7.