Research Article
Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin
Table 2
Half maximal cytotoxic concentration (CC
50) expressed in
M for ivermectin and ivermectin-loaded liposomal formulations.
| | Identification code | Vero-F | Vero-118 | BHK | RAW | Huh-7 |
| | Ivermectin | 23.6 | 5.7 | 1.5 | 0.8 | 10.0 | | 2-cmc | n.d. | 117.3 | 237.7 | 37.6 | n.d. | | #PC3-Ch1-ive0.1 | n.d. | n.d. | n.d. | n.d. | ~10.0 | | #PC3-Cl1-ive0.1 | n.d. | n.d. | n.d. | n.d. | ~10.0 | | #PC3-Br1-ive0.1 | n.d. | n.d. | n.d. | n.d. | >10.0 | | #PC9-Ch1-ive1.0 | >25.0 | >25.0 | 8.4 | 2.2 | ~10.0 | | #PC9-Br0.5-ive1.0 | >25.0 | >25.0 | 8.5 | 2.2 | n.d. | | #PC9-Br1-ive1.0 | >25.0 | >25.0 | 4.3 | 2.2 | ~10.0 | | #PC18-Br1-ive1.0 | >25.0 | >25.0 | >25.0 | >25.0 | n.d. |
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n.d. = not determined; after 48 h of cell culture incubation.
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