Stem Cells Applications in Regenerative Medicine and Disease Therapeutics

Figure 4

MSCs in regenerative medicine: mesenchymal stem cells are CD73⁺, CD90⁺, CD105⁺, CD34⁻, CD45⁻, CD11b⁻, CD14⁻, CD19⁻, and CD79a⁻ cells, also known as stromal cells. These bodily MSCs represented here do not account for MSCs of bone marrow and umbilical cord. Upon transplantation and transdifferentiation these bodily MSCs regenerate into cartilage, bones, and muscles tissue. Heart scar formed after heart attack and liver cirrhosis can be treated from MSCs. ECM coating provides the niche environment for MSCs to regenerate into hair follicle, stimulating hair growth.