Evaluation of Chronic Liver Disease: Does Ultrasound Scoring Criteria Help?
Table 3
(a) Diagnostic performance of US variables in predicting fibrosis/stage. (b) Diagnostic performance of US variables in predicting grade.
(a)
Variable
Sensitivity (95% CI*)
Specificity (95% CI*)
PPV (95% CI*)
NPV (95% CI*)
P value
Liver edge
84.72 (0.74, 0.92)
61.36 (0.46, 0.75)
78.21 (0.67, 0.86)
71.05 (0.55, 0.84)
0.000
Liver surface
54.16 (0.42, 0.65)
86.36 (0.72, 0.94)
86.66 (0.72, 0.94)
53.52 (0.41, 0.65)
0.000
Liver texture
75 (0.63, 0.84)
66 (0.49, 0.79)
78.26 (0.66, 0.86)
61.7 (0.46, 0.75)
0.000
Liver size
12.5 (0.06, 0.22)
77.27 (0.61, 0.88)
47.3 (0.25, 0.70)
35.05 (0.26, 0.45)
0.149
Spleen size
9.72 (0.04, 0.19)
93.2 (0.80, 0.98)
70 (0.35, 0.91)
38.68 (0.29, 0.48)
0.589
Portal vein diameter
5.55 (0.01, 0.12)
39.28 (0.30, 0.48)
0.112
PPV: positive predictive value. NPV: negative predictive value. (95% CI*): 95% confidence internal. value: chi-square test value. : Cannot be calculated because either of one cell contains a “zero."
(b)
Variable
Sensitivity (95% CI*)
Specificity (95% CI*)
PPV (95% CI*)
NPV (95% CI*)
P value
liver edge
80.5 (0.70, 0.88)
64.71 (0.46, 0.79)
84.62 (0.74, 0.91)
57.89 (0.41, 0.73)
0.000
liver surface
51.22 (0.40, 0.62)
91.18 (0.75, 0.97)
93.33 (0.81, 0.98)
43.66 (0.32, 0.55)
0.000
liver texture
72 (0.61, 0.81)
70.6 (0.52, 0.84)
85.51 (0.74, 0.92)
51.06 (0.36, 0.65)
0.000
liver size
14.63 (0.08, 0.24)
79.41 (0.61, 0.90)
63.16 (0.38, 0.82)
27.83 (0.19, 0.38)
0.430
spleen size
9.76 (0.04, 0.18)
94.12 (0.78, 0.98)
80 (0.44, 0.96)
30.28 (0.22, 0.39)
0.499
portal vein diameter
4.88 (0.01, 0.12)
30.36 (0.22, 0.39)
0.190
PPV: positive predictive value. NPV: negative predictive value. (95% CI*): 95% confidence internal. P value: chi-square test P value. : Cannot be calculated because either of one cell contains a “zero."
