Evaluation of Rhubarb Supplementation in Stages 3 and 4 of Chronic Kidney Disease: A Randomized Clinical Trial
Table 2
Haemogram and renal function tests in control and Rhubarb groups before and after 12 weeks of treatment.
Serial number
Parameter
Group
0 week mean ± SD
12 weeks mean ± SD
% change after 12 weeks
95% confidence interval
1
Hb% (g/dL)
I
7.91 ± 1.93
8.91 ± 1.48c
(+) 12.64%
(−) 1.24 to (−) 0.75
II
7.87 ± 2.06
9.05 ± 1.58c1
(+) 14.99%
(−) 1.51 to (−) 0.85
2
FBG (mg/dL)
I
130.05 ± 42.90
113.78 ± 14.31c
(−) 12.51%
8.88 to 23.64
II
132.60 ± 45.55
107.20 ± 18.03c2
(−) 19.15%
14.97 to 35.82
3
PPBG (mg/dL)
I
184.95 ± 61.17
157.56 ± 23.20c
(−) 14.80%
17.38 to 37.40
II
182.30 ± 62.05
147.65 ± 15.46c2
(−) 19.00%
23.17 to 46.11
4
B. Urea (mg/dL)
I
107.16 ± 35.85
79.78 ± 24.79b
(−) 25.55%
21.83 to 32.92
II
108.89 ± 42.65
72.25 ± 20.89c1
(−) 33.64%
30.97 to 42.30
5
S.Cr. (mg/dL)
I
4.44 ± 1.64
3.33 ± 1.37c
(−) 25.00%
0.86 to 1.37
II
4.06 ± 2.08
2.82 ± 1.11 c1
(−) 30.54%
0.91 to 1.55
6
K+ (mEq/L)
I
4.87 ± 0.49
4.63 ± 0.41a
(−) 4.92%
0.27 to 0.41
II
4.84 ± 0.44
4.42 ± 0.48b2
(−) 8.67%
0.26 to 0.57
7
Ca2+ (mg/dL)
I
8.65 ± 1.05
8.89 ± 1.00a
(+) 2.77%
) 0.53 to 0.07
II
8.72 ± 1.01
9.38 ± 0.90b2
(+) 7.56%
(−) 0.93 to (−) 0.38
8
TUP (g/day)
I
3.03 ± 1.29
2.43 ± 0.97b
(−) 19.80%
0.35 to 0.85
II
3.18 ± 1.57
2.12 ± 0.65c1
(−) 30.18%
0.83 to 1.09
9
TUV (mL/day)
I
1454.36 ± 221.53
1736.76 ± 176.04c
(+) 19.41%
(−) 333.40 to (−) 230.38
II
1451.69 ± 303.74
1870.14 ± 258.78c3
(+) 28.82%
(−) 467.28 to (−) 369.61
10
GFR (mL/min)
I
19.0 ± 1.17
23.3 ± 1.63b
(+) 22.6%
5.28 to 9.73
II
19.1 ± 2.37
28.0 ± 3.51c3
(+) 46.5%
5.99 to 15.31
Values are mean ± SD; was considered significant; a, b, c compared to 0 week value of respective group; 1, 2, 3 compared to control group. I: control; II: Rhubarb; Hb%: haemoglobin percent; FBG: fasting blood glucose; PPBG: postprandial blood glucose; B. urea: blood urea; S.Cr.: serum creatinine; K+: serum potassium; Ca2+: serum calcium; TUP: 24 hour total urine protein; TUV: 24 hour total urine volume; GFR: glomerular filtration rate; (−) decrease; and (+) increase.
