Review Article
Magnesium and Human Health: Perspectives and Research Directions
Table 1
Role of vitamins and hormones in magnesium homeostasis.
| Hormone/vitamin | Role of hormones/vitamins | Comments |
| Vitamin D | 1,25-Dihydroxyvitamin D3 can stimulate intestinal magnesium absorption. | Mg is required for metabolism of vitamin D in the liver and the kidneys and also for its transportation in serum. | PTH | Helps in the reabsorption of Mg in the kidney, absorption in the gut, and release from the bone. | Hypercalcemia interferes with the role of PTH in magnesium regulation. | Estrogen | Enhances Mg reabsorption in the kidney and absorption in the gut by stimulating TRPM6 expression. | ā |
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Mg: magnesium; PTH: parathyroid hormone.
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