Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit

Table 5

MICs (μg/mL) for K. pneumoniae R46, its cloned genes, and transconjugant (R46/EC600).

Strain	FFC	CHL	NOR	AMK	NAL	NEO^a	AMP	TCY	TGC^a	RIF	POL	ATM	GEN	CNX	STR	KAN
ATCC 25922	4	4	0.25	2	2	4	8	1	0.25	4	0.5	<0.5	1	0.5	8	2
E. coli C600	8	4	4	1	2	>8	4	0.5	2	1,024	0.5	<0.5	8	1	2	1
Transconjugant (R46/EC600)	512	128	8	1	16	>8	512	512	0.25	512	<0.0625	32	32	<0.0625	>32	512
K. pneumoniae R46	>512	256	8	4	>32	>8	512	512	4	16	1	32	32	1	>32	512
pMD™19-T-floR/DH5α	128	64	<0.0625	<0.0625	2	4	512	0.5	0.25	1	0.25	<0.5	1	0.5	<0.5	2
pMD™19-T-mdfA2/DH5α	32	32	0.25	1	4	4	>512	1	0.25	2	0.25	<0.5	1	0.5	4	2
pMD™19-T-qnrB2/DH5α	8	8	8	2	16	2	>512	1	0.25	8	0.5	<0.5	1	0.5	4	2
pMD™19-T-catB3/DH5α	8	8	<0.0625	2	8	4	>512	1	0.25	2	0.25	<0.5	1	0.5	4	2
E. coli DH5α	8	4	<0.0625	0.5	2	2	<1	0.5	0.25	2	0.25	<0.5	1	0.25	2	2

FFC: florfenicol; CHL: chloramphenicol; NOR: norfloxacin; AMK: amikacin; NAL: nalidixic; NEO: neomycin; AMP: ampicillin; TCY: tetracycline; TGC: tigecycline; RIF: rifampin; POL: polymyxin; ATM: aztreonam; GEN: gentamicin; CNX: cefminox; STR: streptomycin; KAN: kanamycin. ^aFor neomycin and tigecycline, we used EUCAST 2017 as the guideline.