Genus-Wide Comparative Genomics Analysis of Neisseria to Identify New Genes Associated with Pathogenicity and Niche Adaptation of Neisseria Pathogens

Figure 7

Protein-protein interaction of UGNP and UGNGS. N. gonorrhoeae 32867 genome is used as reference. The names of nodes correspond to Table S1. Circular nodes represent the UGNP proteins, and diamond nodes with yellow margin represent the UGNGS proteins. Only the networks with the number of nodes greater than 3 were shown. The network edges represent the protein-protein associations, and their line thickness indicates the confidence of the association between corresponding nodes. The disconnected nodes are hidden in the map. Different colors reflect different protein function categories: red: basic substance transport and metabolism; purple: genetic information processing, including replication, transcription, and translation; blue: cellular processes, including cell wall/membrane/envelope biogenesis and cell motility; green: bacteria-environment interaction, including signal transduction, extracellular structures, and defense mechanism; grey, function unknown.