|
Gene name | Chromosome | Exon | Function | Founder breeds/population | References |
|
LEPR | 3 | 22 | Impact upon blood glucose regulation, milk yield, and milk fat production | Holstein dairy | [34] |
LEP | 4 | 3 | [33–35] |
BDNF | 15 | 6 | Impact upon food intake and thus nutrient and energy availability for milk production | Holstein dairy | [31, 36–39] |
FTO | 18 | 9 |
IGF1 | 5 | 7 |
ABCG2 | 6 | 22 |
GHR | 20 | 13 | Affect growth, proliferation, and apoptosis of cells | Holstein dairy, Ayrshire dairy, Chinese cattle | [34, 40–43] |
PRLR | 20 | 11 |
DGAT1 | 14 | 18 | Involved directly in triglyceride (milk fat) synthesis | Xinong Saanen and Guanzhong goat | [44–47] |
AGPAT6 | 27 | 14 |
RPL3 | 5 | 10 | Regulating energy balance during lactation work | Saanen goat | [12] |
VPS13 | 8 | 73 | Associated with milk production | Saanen goat |
VPS13B | 14 | 65 | Associated with leg morphology, related to fertility and milk production | Holstein dairy | [29] |
VPS13C | 10 | 85 | Act on glucose homeostasis for high milk production | Holstein dairy | [30] |
OPN | 6 | 7 | Milk yield and milk fat production | Holstein dairy | [41, 48] |
BTNA1 | 23 | 9 | Essential for the secretion of milk-lipid droplets | Bamu wild goat, Khonj wild goat, Australian feral rangeland goat, Boer goat, Australian cashmere goat | [27] |
GH1 | 19 | 5 | May stimulate breast development and enhances milk production and associated with milk production | Holstein dairy | [31] |
αs1-casein | 6 | 19 | Major milk protein production and milk formulation | Vallesana, Roccaverano, Maltese, Jonica, and Garganica goat | [8] |
CSN1S2 | 6 | 19 | Encode the major fraction of milk proteins | Sarda goat | [32, 49] |
CSN2 | 6 | 9 |
|