The Clinical Course of Acute Pancreatitis and the Inflammatory Mediators That Drive It
Table 1
Definitions of SIRS, sepsis, and MODS. Modified from American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis, 1992.
Systemic Inflammatory Response Syndrome (SIRS): this response is manifested by two or more of the following conditions:
Temperature >38°C or <36°C
Heart rate >90 beats/min
Respiratory rate >20 breaths/min or PaCO2 <4.3 kPa.
White blood cell count <4,000 or >12,000 cells/mm3, or >10% immature (band) forms.
Sepsis: this response is manifested when two or more of the above conditions occur as a result of infection.
