Research Article
Synthesis and Characterization of Chemically Cross-Linked Acrylic Acid/Gelatin Hydrogels: Effect of pH and Composition on Swelling and Drug Release
Table 7
Effect of degree of cross-linking on drug release kinetics of AA/Gelatin hydrogels in solutions of different pH values.
| Sample codes | EGDMA contents (%) | pH | Zero-order kinetics | First-order kinetics | Higuchi model | (h−1) | | (h−1) | | (h−1) | |
| U7 | 0.65 | 1.2 | 2.052 | 0.984 | 0.025 | 0.987 | 0.0833 | 0.976 | 5.5 | 4.853 | 0.996 | 0.077 | 0.984 | 0.195 | 0.971 | 7.5 | 6.247 | 0.981 | 0.134 | 0.988 | 0.083 | 0.976 |
| U8 | 0.75 | 1.2 | 1.423 | 0.980 | 0.016 | 0.984 | 0.057 | 0.973 | 5.5 | 4.176 | 0.990 | 0.062 | 0.995 | 0.169 | 0.983 | 7.5 | 5.121 | 0.989 | 0.097 | 0.966 | 0.211 | 0.993 |
| U9 | 0.85 | 1.2 | 1.412 | 0.977 | 0.016 | 0.983 | 0.058 | 0.993 | 5.5 | 4.019 | 0.997 | 0.056 | 0.994 | 0.160 | 0.963 | 7.5 | 5.251 | 0.992 | 0.090 | 0.989 | 0.212 | 0.978 |
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