Synthesis and Characterization of Chemically Cross-Linked Acrylic Acid/Gelatin Hydrogels: Effect of pH and Composition on Swelling and Drug Release

Table 8

Effect of different concentration of acrylic acid on drug release mechanism of AA/Gelatin hydrogels in solutions of different pH values using EGDMA as cross-linking agent (0.7% of acrylic acid).

Sample codes	AA contents (%)	pH	Release exponent ()		Order of release
U4	28	1.2	0.7162	0.995	Non-Fickian
		5.5	0.9463	0.997	Non-Fickian
		7.5	0.9257	0.991	Non-Fickian
U5	32	1.2	0.7532	0.994	Non-Fickian
		5.5	0.9832	0.994	Non-Fickian
		7.5	0.9573	0.992	Non-Fickian
U6	36	1.2	0.7261	0.987	Non-Fickian
		5.5	0.8643	0.990	Non-Fickian
		7.5	0.8252	0.985	Non-Fickian