Behcet’s Disease: Is There Geographical Variation? A Review Far from the Silk Road

Table 5

Summary of recommended treatment [41, 42].

Manifestation	Treatment
Mucocutaneous
Mild	Topical steroids
Moderate to severe	Initial:
	Systemic steroid
	Colchicine
	Refractory case:
	Azathioprine
	Interferon α
Eye	Initial:
	Systemic steroid + azathioprine
	Refractory case:
	(1st) Cyclosporine A + steroid + azathioprine
	(2nd) Interferon α +/− systemic steroid
Arthritis	(1st) Colchicine
	Nonsteroidal anti-inflammatory drug
	(2nd) Azathioprine
	Interferon
Vessels
Deep venous thrombosis	Azathioprine
	Cyclosporine A
	Cyclophosphamide (larger vessels)
Arterial aneurysm	Cyclophosphamide + systemic steroid
Neurological	Cyclophosphamide (drug of choice)
	Cyclosporine A (contraindicated)
Gastrointestinal	Systemic steroid
	Sulfasalazine
	Azathioprine