Journal of Addiction / 2019 / Article / Tab 3 / Clinical Study
Suboxone Treatment and Recovery Trial (STAR-T): Study Protocol for a Randomised Controlled Trial of Opioid Medication Assisted Treatment with Adjunctive Medication Management Using Therapeutic Drug Monitoring and Contingency Management Table 3 Interventions under study groups (TDM; TAU).
Intervention Randomisation Group TDM TAU Induction Yes Yes Stabilisation Yes Yes Baseline assessments Yes Yes Estimating BUP Elimination Rate Yes Yes Medication education Yes Yes Emergency card Yes Yes Outpatient DOT Yes No Outpatient medication management manualised intervention Yes No UDS at outpatient care Yes Yes Providing prescription take-home doses Contingent on UDS & TDM (i.e., abstinence & adherence) Contingent on UDS only Stepped BUP/NX-F take-home doses Yes No Maximum take BUP/NX-F home doses 4 weeks 2 weeks TDM Yes No Periodic study assessments Yes Yes End of study assessments Yes Yes Psychosocial support Yes Yes
BUP: buprenorphine; DOT: directly observed treatment; UDS: urinary drug screen; TDM: therapeutic drug monitoring.