Development of an HPLC-UV Method for the Analysis of Drugs Used for Combined Hypertension Therapy in Pharmaceutical Preparations and Human Plasma

Table 4

Absolute and relative recoveries of plasma analysis.

	Concentration of AML; (𝜇g/mL)			Concentration of OLM; (𝜇g/mL)			Concentration of VAL; (𝜇g/mL)			Concentration of HCT; (𝜇g/mL)
	0.5	10	18	0.5	15	25	0.5	10	15	0.8	10	20
Absolute recovery %	77.3	81.6	80.2	73.5	74.2	77.6	75.8	78	80.8	79.6	81.3	80
RSD%	4.5	3.7	3.5	2.6	2.5	1.8	4.2	3.9	2.5	2.7	1.7	1.6
Relative recovery %	95.5	97.6	97.9	92.6	95.8	96.7	100.3	99.8	98.7	92.7	100.3	100.1
RSD%	3.3	3.7	2.9	2.8	3.2	3.1	1.9	2.6	2.3	4.7	3.2	3.5