Clinical Study

Effect of a Nurse-Led Diabetes Self-Management Education Program on Glycosylated Hemoglobin among Adults with Type 2 Diabetes

Table 2

Two-way ANOVA with repeated measures for primary and secondary outcomes.

ModelIntervention mean (SD)Control mean (SD)Significance
value valueEffect size (Eta square)

HbA1c9.3 (1.06)8.6 (1.01)7.9 (0.93)9.3 (1.1)9.3 (1.1)9.3 (1.1)
Group14.50.09
Time277.60.66
Group × time289.50.67
Systolic blood pressure130.7 (9.4)129.3 (9.1)127.8 (9)133.9 (12.3)133.7 (12.1)133.3 (12)
Group5.90.010.04
Time59.10.29
Group × time25.70.15
Diastolic blood pressure85.8 (0.69)84.7 (0.67)83.4 (0.65)87.3 (0.69)87.3 (0.67)87.1 (0.65)
Group7.40.05
Time61.30.30
Group × time39.30.21
Weight82.58 (11.08)82.21 (11.09)82 (10.89)83.75 (10.93)83.77 (10.91)83.82 (10.89)
Group0.680.410.01
Time4.690.010.03
Group × time7.170.010.04
BMI28.69 (3.2)28.54 (3.2)28.55 (3.2)28.87 (3.4)28.87 (3.4)29.89 (3.4)
Group0.240.620.01
Time2.590.070.01
Group × time3.180.040.02
Triglyceride142.83 (34.4)141.66 (33.9)140.90 (33.7)142.09 (35.7)142.04 (35.6)142.01 (35.6)
Group0.000.960.01
Time40.410.22
Group × time33.820.19
Cholesterol173.1 (45.4)171.3 (43.8)169.09 (43.1)171.9 (48.4)170.7 (47.02)171.88 (46.8)
Group0.0060.930.01
Time3.150.060.02
Group × time0.100.820.01
LDL95.89 (30.04)95.59 (28.4)93.95 (27.9)92.68 (25.6)93.06 (25.4)94.15 (25)
Group0.160.680.01
Time0.150.850.01
Group × time5.620.220.39
HDL53.68 (12.8)54.72 (11.6)55.38 (11.8)53.21 (12.4)53.21 (12.5)52.76 (12.6)
Group0.550.450.01
Time2.660.280.01
Group × time6.940.940.04
Efficacy expectation98.35 (13.95)113.47 (11.07)123.47 (11.31)98.06 (17.47)99.77 (14.48)98.44 (15.69)
Group34.30.19
Time152.20.52
Group × time138.70.49
Outcome expectation57.80 (7.11)62.85 (5.50)66.79 (5.35)58.11 (7.50)58.04 (7.33)58.16 (7.23)
Group16.150.10
Time150.810.51
Group × time147.610.51
DSMB3.56 (1.22)4.67 (1)5.41 (1.15)3.71 (1.40)3.67 (1.37)3.73 (1.40)
Group16.70.10
Time228.50.62
Group × time221.60.61
QOL50.42 (9.17)50.76 (9.06)50.67 (9.04)50.69 (8.90)50.34 (8.83)50.39 (8.71)
Group0.000.920.01
Time0.070.860.01
Group × time10.50.07
Social support52.63 (9.31)54.33 (9.42)55.37 (9.61)55.83 (12.11)55.82 (12.63)55.91 (12.75)
Group0.880.340.01
Time43.60.23
Group × time39.30.21
Depression12.15 (4.99)11.98 (4.97)11.95 (5.03)12.76 (4.66)12.84 (4.61)12.91 (4.50)
Group10.310.01
Time0.510.550.01
Group × time9.330.100.06

Note: Group: test of between-subject effects; Time: test of within-subject effect; Group × time: interaction between group by time; SD: standard deviation; : baseline measurement; : 3-month measurement; : 6-month measurement; DSMB: diabetes self-management behavior; LDL: low-density lipoprotein; HDL: high-density lipoprotein; BMI: body mass index; QOL: quality of life; Primary outcome: HbA1c. To interpret effect sizes, 0.02 be considered a “small magnitude,” 0.15 be considered a “medium magnitude,” and 0.35 be considered a “large magnitude” [52].