Prophylactic mRNA Vaccination against Allergy Confers Long-Term Memory Responses and Persistent Protection in Mice

Figure 1

Phl p 5-specific IgG1 (a), IgG2a (b), and IgE (c) antibodies one week after sensitization. BALB/c mice were prevaccinated or left untreated and sensitized with recombinant Phl p 5 after the indicated time interval. Data are shown as relative light units of a luminometric ELISA or as percentage of total release induced by addition of 10% Triton X-100 and presented as means ± SEM (). ; .

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(b)

(c)