Prophylactic mRNA Vaccination against Allergy Confers Long-Term Memory Responses and Persistent Protection in Mice

Figure 4

Time course of Phl p 5-specific IgG1 (a), IgG2a (b), and IgE (c) antibody levels as measured by a luminometric ELISA or RBL assay, respectively. BALB/c mice were prevaccinated and sensitized one month later, followed by monthly exposure to aerosolized rPhl p 5. Data are displayed as means ± SEM ().

(a)

(b)

(c)