Research Article

Comparison of RPR and ELISA with TPHA for the Diagnosis of Syphilis: Implication for Updating Syphilis Point-of-Care Tests in Ethiopia

Table 1

The detection of syphilis by Randox-TPHA reactivity among study participants at University of Gondar Hospital, 2015–2016.

DemographyTotal (%)Randox-TPHA Positive (%)Randox-TPHA Negative (%)COR (95% CI)AOR (95% CI)

GenderMale84 (52.5)33 (39.3)51 (60.7)1.11 (0.58–2.10)1.15 (0.59–2.25)
Female76 (47.5)28 (36.8)48 (63.2)11
1111111
Age (years)20–30121 (75.6)48 (39.7)73 (60.3)0.76 (0.35–1.66)0.75 (0.34–1.67)
31–4036 (22.5)12 (33.3)24 (66.7)11
≥413 (1.9)1 (33.3)2 (66.7)N/A N/N/AN/A
ResidenceUrban53 (33.1)19 (35.8)34 (64.2)0.86 (0.44–1.71)0.90 (0.44–1.83)
Rural107 (66.9)42 (39.3)65 (60.711

N/A: not considered during analysis; TPHA: T. pallidum hemagglutination assay; COR: crude odds ratio; AOR: adjusted odds ratio; CI: confidence interval; %: percent.