Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding

<div>Effect of butyrate on secreted IL-8 from Caco-2 monolayers stimulated with IL-1<i>β</i> and ethanol. Human intestinal epithelial cells (Caco-2) were grown to confluency in 24-well plates, and monolayers were allowed to differentiate for 7 days. Cells were pretreated ± sodium butyrate (5 mM) for 18 h and then challenged with 25 mM ethanol and/or 10 ng/mL IL-1<i>β</i> for 3 h. Extracellular media was then collected and analyzed for IL-8 by ELISA. Treatments were performed in duplicate and repeated four times. 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Journal of Immunology Research

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Figure 3

Figure 3: Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding 

Figure 3 | Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding 