Review Article

Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines

Table 3

Status of development of some intradermal vaccines.

PathogenFormulation/antigenIndicationClinical trial statusClinical trial IDRefs

Influenza virusSplit virusInfluenzas A and BApprovedNCT01712984, NCT02563093, NCT02258334, NCT01946438[118]
Enterotoxigenic E. colidmLTGastroenteritisPhase 1NCT02531685[119]
HBVHBsAgHepatitis BPhase 1NCT02186977[120]
Dengue virusAttenuated virusDengue feverPhase 1NCT01765426[121]
PoliovirusInactivated virusPoliomyelitisPhase 3NCT03239496[122]
HIV-1HIV-1 DNAAIDSPhase 2aPACTR2010050002122368[123]

dmLT: double mutant heat-labile enterotoxin.