Atypical Mucin Expression Predicts Worse Overall Survival in Resectable Pancreatic Ductal Adenocarcinoma

Figure 1

The expression patterns of mucins in PDAC tissues. (a) mRNA expression level of mucins in the QCMG PDAC cohort (). (b–g) Low-power-field images showing the representative positive and negative results of IHC staining mucins’ expression in the FUSCC PDAC cohort. Corresponding high-power-field images were displayed in Supplementary Figure 1. (b, c) MUC1-positive expression was only considered when positive coloration located in the apical membrane of PDAC cells; (d, e) MUC2-positive expression was only considered when positive coloration was located in the cytoplasm of PDAC cells. (f, g) MUC5AC-positive expression was only considered when positive coloration was located in the cytoplasm of PDAC cells. Abbreviations: TPM: transcripts per million reads; PDAC: pancreatic ductal adenocarcinoma.

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