Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction (WISE-CVD)
Table 2
A comparison of coronary reactivity measures in the original and contemporary WISE cohorts.
Endothelial-Independent Reactivity (Δ Diam to NTG)
n=113
n=170
Mean Δ Diam
9.8 ± 13.5
9.7 ± 13.0
0.94
Median (IQR)
8.3 (2.8, 17.1)
7.6 (1.3, 18.8)
0.87
% with Δ Diam ≤ 20% (abnormal)
83
78
0.28
p-values by t-test, Kruskal-Wallis test, and Chi Square, where appropriate. CFR-Ado = coronary flow reserve in response to adenosine; IQR=inter-quartile range; ACH = acetylcholine; NTG = nitroglycerin.