Nonemergent Percutaneous Coronary Intervention on an Unprotected Left Main Coronary Artery Supported with Impella® Heart Pump in Patients Ineligible for Surgical Revascularization
Table 1
Baseline characteristics.
Characteristics
All
CABG ineligible
CABG eligible
p-value
(N=331)
(N=227)
(N=104)
Demographics
Age
72.72±11.35 (331)
72.16±11.23 (227)
73.92±11.55 (104)
0.191
Gender - Male
67.07% (222/331)
69.60% (158/227)
61.54% (64/104)
0.166
BSA (m2)
1.94±0.27 (317)
1.96±0.28 (218)
1.90±0.26 (99)
0.058
Baseline Characteristics
Hyperlipoproteinaemia
74.92% (245/327)
72.12% (163/226)
81.19% (82/101)
0.097
Hypertension
89.43% (296/331)
88.11% (200/227)
92.31% (96/104)
0.336
Diabetes Mellitus
48.16% (157/326)
47.35% (107/226)
50.00% (50/100)
0.719
CAD
75.00% (225/300)
75.36% (159/211)
74.16% (66/89)
0.884
Angina
35.43% (107/302)
34.76% (73/210)
36.96% (34/92)
0.794
Stroke
8.81% (26/295)
9.71% (20/206)
6.74% (6/89)
0.506
Renal Insufficiency
27.69% (90/325)
26.55% (60/226)
30.30% (30/99)
0.503
Dialysis
27.85% (22/79)
28.30% (15/53)
26.92% (7/26)
1.000
Liver Insufficiency
2.45% (7/286)
2.94% (6/204)
1.22% (1/82)
0.677
COPD
30.96% (100/323)
34.07% (77/226)
23.71% (23/97)
0.068
Arrhythmia
27.69% (90/325)
25.22% (57/226)
33.33% (33/99)
0.140
PVD
26.85% (87/324)
26.11% (59/226)
28.57% (28/98)
0.683
CHF
51.31% (157/306)
48.58% (103/212)
57.45% (54/94)
0.173
NYHA Class III/IV
62.28% (71/114)
64.00% (48/75)
58.97% (23/39)
0.685
Prior AICD/Pacer Implanted
13.94% (46/330)
10.18% (23/226)
22.12% (23/104)
0.006
Valvular Disease
17.05% (52/305)
16.98% (36/212)
17.20% (16/93)
1.000
Prior MI
47.99% (155/323)
44.89% (101/225)
55.10% (54/98)
0.115
Prior PCI
41.16% (135/328)
40.71% (92/226)
42.16% (43/102)
0.810
Prior CABG
0.00% (0/331)
0.00% (0/227)
0.00% (0/104)
- -
Surgical consultation was requested
58.23% (191/328)
66.08% (150/227)
40.59% (41/101)
<.001
LVEF
34.97±17.38 (293)
36.05±17.80 (199)
32.69±16.30 (94)
0.123
STS Mortality Score
6.09±6.57 (305)
6.15±6.83 (208)
5.96±6.01 (97)
0.813
STS Morbidity Score
30.25±17.56 (305)
30.26±18.23 (208)
30.21±16.12 (97)
0.980
Hemodynamics
Heart Rate (bpm)
73.01±16.58 (324)
72.66±15.45 (221)
73.75±18.83 (103)
0.610
Systolic Blood Pressure (mmHg)
125.50±24.26 (323)
124.86±24.24 (219)
126.85±24.37 (104)
0.492
Diastolic Blood Pressure (mmHg)
68.37±15.20 (323)
68.00±15.45 (219)
69.13±14.69 (104)
0.532
Mean Arterial Pressure (mmHg)
88.12±16.42 (323)
88.24±16.53 (219)
87.87±16.27 (104)
0.849
Hematology and Blood Chemistry
RBC (106/μL)
3.92±0.88 (297)
3.91±0.95 (201)
3.94±0.71 (96)
0.728
WBC (103/μL)
8.42±3.65 (300)
8.34±3.86 (204)
8.57±3.16 (96)
0.579
Hgb (g/dL)
12.47±10.33 (310)
12.82±12.38 (208)
11.77±3.41 (102)
0.260
HCT (%)
34.99±5.55 (308)
34.99±5.62 (207)
34.99±5.42 (101)
0.997
Platelet Count (103/μL)
205.03±66.81 (303)
204.05±68.84 (205)
207.10±62.66 (98)
0.711
Total Bilirubin (mg/dL)
0.79±0.97 (93)
0.75±0.94 (62)
0.89±1.05 (31)
0.500
Creatinine (mg/dL)
1.49±1.22 (268)
1.51±1.22 (183)
1.44±1.21 (85)
0.635
eGFR (mL/min/m2)
56.49±25.00 (128)
56.52±25.43 (86)
56.43±24.42 (42)
0.985
AST (U/L)
45.22±72.84 (101)
40.16±77.03 (70)
56.65±62.01 (31)
0.296
ALT (U/L)
33.96±47.52 (102)
28.90±18.27 (70)
45.03±80.19 (32)
0.269
AICD: automatic implantable cardioverter defibrillator; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CABG: coronary artery bypass grafting; CAD: coronary artery disease; CHF: chronic heart failure; NYHA: New York Heart Association; COPD: chronic obstructive pulmonary disease; eGFR: estimated glomerular filtration rate; Hgb: hemoglobin; HCT: hematocrit; LVEF: left ventricular ejection fraction; MI: myocardial infarction; PCI: percutaneous coronary intervention; PVD: peripheral vascular disease; RBC: red blood cells; STS: Society of Thoracic Surgeons; TIMI: thrombolysis in myocardial infarction; WBC: white blood cells.
