Overconsumption of Omega-6 Polyunsaturated Fatty Acids (PUFAs) versus Deficiency of Omega-3 PUFAs in Modern-Day Diets: The Disturbing Factor for Their “Balanced Antagonistic Metabolic Functions” in the Human Body

<div>Biosynthesis of Omega-3 and Omega-6 PUFAs is shown at the center. The oxidative metabolism of LA, DGLA, AA, EPA, and DHA into their respective lipid mediators through oxygenase enzymes is also shown in the right and left sides. COX: cyclooxygenase; LOX: lipoxygenase; MPO: myeloperoxidase [<a href="/journals/jl/2021/8848161/#B19">19</a>, <a href="/journals/jl/2021/8848161/#B33">33</a>, <a href="/journals/jl/2021/8848161/#B48">48</a>, <a href="/journals/jl/2021/8848161/#B60">60</a>].</div>

Journal of Lipids

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Figure 3: Overconsumption of Omega-6 Polyunsaturated Fatty Acids (PUFAs) versus Deficiency of Omega-3 PUFAs in Modern-Day Diets: The Disturbing Factor for Their “Balanced Antagonistic Metabolic Functions” in the Human Body 

Figure 3 | Overconsumption of Omega-6 Polyunsaturated Fatty Acids (PUFAs) versus Deficiency of Omega-3 PUFAs in Modern-Day Diets: The Disturbing Factor for Their “Balanced Antagonistic Metabolic Functions” in the Human Body 