Genotoxic Effects of Etoposide, Bleomycin, and Ethyl Methanesulfonate on Cultured CHO Cells: Analysis by GC-MS/MS and Comet Assay

Figure 4

GC-MS/MS—comparison of the induction of (a) FapyGua, (b) 8-OH-Gua, and (c) 5-OH-MeUra by bleomycin. The data are plotted as the mean and standard deviation of 4 separate replicates, performed in parallel, as described in Materials and Methods. Statistical analysis is given in Table 2.

(a)

(b)

(c)