Gold Nanoparticle Mediated Phototherapy for Cancer

Figure 8

In vivo fluorescence imaging of AuNP-Pc 4 conjugates. Tumor-bearing mice were injected intravenously with AuNP-Pc 4 conjugates at a Pc 4 dosage of 1 mg kg-1 mouse. (a) In vivo fluorescence imaging of a AuNP-Pc 4 conjugate injected mouse at various time points within 24 h. Arrows indicate tumor location. (b) The average fluorescence intensities from the tumor areas of 24-h postinjection mice (). (c) Picture of the tumor at 4 h after injection (left) and the corresponding 3D surface plot (right) of pixel intensities (Pc 4 fluorescence) obtained from ImageJ. (d) Comparison of the fluorescence images in whole versus transected tumors at 4 h, 24 h, and 7 days after injection. Reprinted with permission from [46]. Copyright (2011) American Chemical Society.

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